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How human chorionic gonadotropin injection (HCG) for fertility is injected?

How human chorionic gonadotropin injection (HCG) for fertility is injected?

Human chorionic gonadotropin or HCG is mainly a hormone that is secreted by specialized cells known as trophoblasts early in pregnancy. Later this type of hormone is made by the placenta.

You need to know that HCG injections are sometimes used in fertility treatments to help an egg to mature and discharge from the ovary for intrauterine insemination or egg retrieval.

HCG is helpful in maintaining high levels of progesterone which is important for the success of the pregnancy. Human chorionic gonadotropin is also the hormone that is identified by urine and blood pregnancy tests.

How HCG is produced during pregnancy?

In pregnant women, the HCG hormone is a glycoprotein that is produced by the placenta during the first pregnancy weeks. This further help to produce progesterone and stop menstruation.

As time passes, HCG increase during the first 10 weeks of pregnancy, and their levels double every 48 or 72 hours.

What is the purpose of HCG injections?

Female infertility

The common FDA-approved use of HCG as an injection is to treat infertility in women. When you find difficulty in conceiving, your doctor might prescribe HCG in combination with other medicines like menotropins and urofollitropin in order to boost fertility.

You need to know that HCG can act similarly to luteinizing hormone (LH), a chemical produced by your pituitary gland that is responsible for encouraging ovulation. 

Keep one thing in mind, some fertility problems occur in women who have trouble producing LH. As LH arouses ovulation and ovulation is important for pregnancy.  As a woman, if you are undergoing in-vitro fertilization (IVF), then the doctor might prescribe HCG to boost your body’s likelihood of keeping a pregnancy. 

When HCG is injected?

The HCG injection is given under various conditions:

  • To treat female infertility
  • Stimulate ovulation in IVF or IUI procedures
  • To treat male hypopituitarism
  • Diagnose and treat cryptorchidism in adolescent boys
  • Diagnose male hypogonadism
  • Prevent miscarriage and ovarian cysts

When do you need to take HCG injection?

This medicine is taken when there is a mature egg follicle in your ovary. The doctor will tell you a particular time or time frame in which the HCG injection should be taken. It is vital to inform the doctor if you are not able to take this injection on time.

After you inject HCG and involve in intercourse or intrauterine insemination then ovulation will take place in almost 36 hours. The day you get this injection and the two days following it are important days for you.

What are the early symptoms of pregnancy after you take HCG injections?

Due to the boosted human chorionic gonadotropin level at the time of pregnancy, pregnant women can experience breast tenderness, light spotting, nausea, mood swings, or bloating in the first 2 weeks.

What is the dosage of human chorionic gonadotropin injections?

The average human chorionic gonadotropin activate shot dosage for female infertility treatments is 5000 and 10000 units. Though this dosage might look high, but your doctor will give the right HCG intramuscular or subcutaneous injection plan.

The dosing of HCG injection is to boost sperm in men by almost 1,000 to 4,000 units.

Where and how to inject human chorionic gonadotropin injection?

Depending upon whether the vial is liquid or powder, HCG injection is given in diverse techniques. You need to know that liquid HCG vials must be refrigerated within 3 hours after buying them from a drugstore. It should not be removed from the refrigerator except at the time of injection.

It is necessary to know that the non-refrigerated HCG liquid must not be injected into your body under no conditions. Direct injection of HCG cold liquid might cause you discomfort. So, it is better to increase the temperature of the vial by simply holding it between your hands before injection. 

On the other hand, the powdered form of HCG can be easily kept at room temperature. At the time of injection, you need to draw 1cc of bacteriostatic water into the syringe, pour it into the powdered vial, then start rotating it slowly. Do not prepare the solution with tap water or mineral water.

Powder and water are mixed together by rolling the vial between hands that contain the solution. Remember shaking the vial can decrease the effects of HCG.

The HCG injection is given in the required area as directed by the doctor after the solution into the syringe is drawn and the air is removed.

What interacts with HCG injection?

Some herbal supplements like black cohosh, blue cohosh, or chaste berry can interact with HCG injection. However, this is not the complete list of possible interactions.

Make sure you inform the doctor about all other medicines, prescription & non-prescription drugs, herbal supplements, and other dietary supplements you take (if any).

In case, you smoke, use illegal drugs, or drink alcohol, inform the doctor beforehand. There are some items that might interact with HCG injection.

Is HCG injection safe for you?

Remember not all people are considered good candidates for HCG injection. This medication is not recommended for people with the following conditions:

  • Drug sensitivity
  • Asthma
  • Abnormal uterine bleeding
  • Pregnancy or suspecting pregnancy
  • Kidney disease
  • Epilepsy
  • Allergic reaction to HCG
  • Cardiovascular diseases
  • Prostate cancer
  • Cyst in the ovaries

In case, you suffer from any of these problems then inform the doctor beforehand to avoid complications.

Are there any risks and side effects of HCG injection?

Just like other medicines, HCG injection can also cause some risks and side effects. Some of them are stated below:

  • Depression
  • Allergic reactions
  • Mood swings
  • Pain, mainly in your lower abdominal
  • Fatigue
  • Sudden weight gain
  • Increased irritability
  • Headache

If you find these side effects worsen or continue, meet the doctor once.

Therefore, HCG injection is the best and safe option for various fertility treatments like IUIs, IVF, and others.