Vardenafil Vs Sildenafil for Erectile Dysfunction: A Comprehensive Guide
Both Vardenafil and Sildenafil are PDE5 inhibitors that treat erectile dysfunction; they relax blood vessels and improve blood flow to the penis.
Though their effects are similar, understanding these distinctions can help you choose the right option.
Let's explore more details about Vardenafil and Sildenafil and find out the key differences between these ED drugs.
Vardenafil vs. Sildenafil
Vardenafil is popular as Levitra, and Sildenafil as Viagra, and you can buy these ED medicines under these brand names.
Both Viagra (Sildenafil) and Levitra (Vardenafil) treat erectile dysfunction or male impotence and are taken before sexual activity. While both require a prescription, consulting a doctor before use is advised.
Viagra lasts about four hours, while Levitra works for four to six hours. Levitra is less affected by food, whereas a high-fat meal can delay Viagra’s effects.
How Do Dosage and Usage Differ Between Vardenafil and Sildenafil?
Understanding the difference in dosage and usage of Vardenafil and Sildenafil can help you choose the ideal drug for you to treat your ED symptoms. Below, we have listed the standard dosage, onset time and duration effects of Vardenafil vs. Sildenafil:
Comparison of Vardenafil and Sildenafil Dosage:
Vardenafil dosage is usually lower in milligrams but is still more potent than Sildenafil Dosage as per mg. In comparison, Sildenafil requires higher dosages to achieve similar vasodilation effects to beat Vardenafil effects.
| Medication | Typical Starting Dose | Available Dosages | Max Daily Dose |
|---|---|---|---|
| Vardenafil | 10 mg orally | 5 mg, 10 mg, 20 mg | 20 mg |
| Sildenafil | 50 mg orally | 25 mg, 50 mg, 100 mg | 100 mg |
Vardenafil vs. Sildenafil: Time to Onset
Regarding onset timing, Vardenafil kicks slightly faster than Sildenafil, especially when taken on an empty stomach. While Sildenafil may have delayed results when taken after a high-fat meal. So, using Sildenafil after a meal can make a difference; it would be best to eat a light meal while taking Sildenafil.
| Drug | Onset Time (Approx.) | Food Impact |
|---|---|---|
| Vardenafil | 25–60 minutes | Slight |
| Sildenafil | 30–60 minutes | Significant |
Duration of Effect: Vardenafil vs. Sildenafil
Vardenafil has slightly longer-lasting effects and maintains its effectiveness even after several hours of ingestion. While sildenafil peaks earlier at some point, both drugs have similar effective durations.
| Drug | Duration of Action | Peak Effect |
|---|---|---|
| Vardenafil | 4 to 6 hours | ~1 hour |
| Sildenafil | 4 to 5 hours | ~1–2 hours |
How effective are Sildenafil and Vardenafil pills?
Vardenafil (Levitra) is 10 times more biochemically potent than Sildenafil (Viagra). Even a lower dose of Vardenafil can help facilitate penile erection, resulting in fewer side effects.
What Are the Side Effects of Sildenafil and Vardenafil?
Along with medical benefits, Sildenafil and Vardenafil may also lead to some common side effects, including:
- Headache
- Flushing
- Diarrhea
- Nausea
- Dizziness
These effects are usually temporary and don't usually require medical attention. Seek medical care if they persist or worsen.
However, there are also some rare side effects which can be serious. Sildenafil is more likely to cause visual disturbances, such as blurred vision or blue-tinted sight, due to its partial effect on PDE6 in the retina. Find out: Why Viagra causes colorued vision in some cases. Vardenafil tends to be better tolerated visually, with fewer reports of eye-related side effects.
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Vardenafil vs. Sildenafil: Drug Interactions & Precautions
Both Vardenafil (Levitra) and Sildenafil (Viagra) interact with certain medications and health conditions and require caution.
Dangerous Interactions:
Avoid nitrates drugs (e.g., nitroglycerin) due to the risk of severe blood pressure drops. These PDE5 inhibitor drugs also interact with alpha-blockers, protease inhibitors, antifungals, and certain antibiotics, which may increase the risk of side effects.
Health Risks:
Patients with heart disease, recent heart attack or stroke, kidney/liver impairment, or unstable angina should consult a doctor before use. Older adults should use lower doses.
Alcohol Caution:
Excessive alcohol can cause dizziness, fainting, and low blood pressure. While small amounts are generally safe, alcohol and nitrates must never be combined with ED drugs.
Vardenafil vs. Sildenafil: Which One Is Better for You?
The choice between Sildenafil (Viagra) and Vardenafil (Levitra) depends on timing, health factors, and your personal preference:
Onset & Food Sensitivity
- Vardenafil: It works faster (25–45 min) and is less affected by food, making it ideal for spontaneity.
- Sildenafil: It takes 30–60 min, may be delayed by high-fat meals, and might need more planning.
Age, Health & Side Effects
- Vardenafil: It is a better choice for older adults, those with mild kidney/liver issues, or vision sensitivity.
- Sildenafil: It may suit younger, healthy individuals who can tolerate stronger peak effects well.
Frequent alcohol or high-fat meal consumers may prefer Vardenafil(Levitra) Tablets for more consistent results.
Doctor’s Advice and Your Preference
- Sildenafil is often the first choice due to its longer track record and affordability, and many men prefer it.
- Vardenafil: It may be preferred by those experiencing side effects like blurred vision from Sildenafil.
Conclusion:
Medical history, side effects, and lifestyle determine the best choice for you among these ED pills. Consult a doctor for guidance and choose your ideal dose of any of the ED pills that suits you best.