Interaction Between Cialis And Grapefruit

Interaction Between Cialis And Grapefruit
Published : Feb 04, 2024
Last Updated : Mar 07, 2024

Cialis is one of the most popular and effective erectile dysfunction drugs. It is an FDA-approved drug that contains an active salt called Tadalafil. This medicine is a PDE-5 inhibitor and helps increase blood flow to the penis.

Cialis improves erectile function and sexual satisfaction in men with Erectile dysfunction. Not only does it treat ED, but the active ingredients of this ED medicine also help treat BPH. Benign prostatic hyperplasia (BPH) is an enlarged prostate that causes urinary symptoms.

In addition, Tadalafil helps manage the symptoms of pulmonary arterial hypertension, a high blood pressure that affects the small arteries of the lungs.

This oral ED medicine is usually taken like other medicines, but you should take it 1 hour before sex. You can take it with food or on an empty stomach; It is up to you how you like to take it. However, most of the questions raised about using Cialis with Grapefruit are because of their interaction.

However, Cialis's effect may be affected if you take it with Grapefruit. In this article, we will discuss whether grapefruit affects Cialis's performance and provide some more information related to grapefruit and Cialis's interaction and its consequences.

Related Article: Does Cialis(Tadalafil) Lower Blood Pressure?

How can Grapefruit affect Cialis?

If you are thinking of taking your Cialis dose with a glass of grapefruit juice, there are better ideas than this. It is better to choose a glass of water or orange juice.

The study published in the American Journal of Cardiovascular Drugs shows that grapefruit juice may cause interaction with certain drugs. Erectile dysfunction medication like Cialis is one of them.

Do you know what a drug interaction is? Let's explain it to you. A drug interaction occurs when the effects of one drug are altered by another drug when you take them together or at the same time. This interaction among the drugs may enhance the benefits or reduce the effectiveness of the drugs. In some cases, the interaction can lead to unwanted side effects, which can be toxic.

The same happens in the case of Grapefruit and Cialis. Grapefruit with Cialis, when used together, may produce unwanted effects of this drug.

As you now know, Cialis(Tadalafil) is a PDE-5 inhibitor, and it acts as a vasodilator. The primary purpose of the drug is to improve blood flow to the penis and help a man get an erection. But when combined with Grapefruit, the effects of the drug appear differently.

Grapefruit can increase the amount of Cialis in the body. It happens when the Grapefruit prevents systemic metabolism. It is a process in which the concentration of Cialis gets reduced before reaching the bloodstream. An enzyme called(CYP 3A4) in your intestine is responsible for this metabolism. And, when Grapefruit inhibits it, there can be a higher amount of Cialis in the body.

The higher concentration of Cialis(Tadalafil) in the body may increase its effectiveness, but it also increases the risk of side effects.

Not only with Cialis Oral Tablets, but similar effects may also appear when you take Grapefruit with other Ed drugs and antihypertensives. Grapefruit also interacts with popular Ed drugs like Viagra (Sildenafil) and Vardenafil.

So, it would be best to avoid eating Grapefruit or drinking grapefruit juice around the time you take Cialis.

Effects of Grapefruit on Generic Cialis(Tadalafil)

You can get unwanted effects when you consume Grapefruit with generic cialis, such as Tadacip oral tablets or Vidalista 20mg. You may come across heightened side effects of Cialis that can be toxic.

We have noted that Tadalafil is also used to control pulmonary arterial hypertension. Side effects from such conditions can be severe and dangerous if left untreated.

So make sure to consult a doctor soon if you experience side effects such as:

  • Headache
  • Muscle pain
  • Memory issue
  • Shortness of breath
  • Fainting
  • Irregular heartbeat

If you experience any of these side effects, contact a doctor and seek medical care immediately.

How long can Grapefruit affect Cialis?

In a study published by American Family Physician, an 8oz glass of Grapefruit can stay up to 72 hours in your digestive system.

So, drinking or eating Grapefruit or its juice for 3 days is not recommended before taking this Ed medication.

If you take Cialis daily for the treatment, which is 5mg per day, you should not consume grapefruit at all. Also, consult a doctor before to learn more about possible tadalafil interactions.

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Last lines:

Cialis is highly recommended for men who are facing the symptoms of impotence. This ED medicine, with its effectiveness, manages the symptoms of ED in no time. It improves blood flow to various body parts and has other medical benefits besides ED.

However, people taking Cialis should be aware of the potential interaction of Tadalafil. Grapefruit is among the foods that can interact with Cialis. You should avoid using Grapefruit while taking this ED drug to prevent its effect on Cialis.

Learn more about Tadalafil, its effects on your body, and possible interactions by talking with your doctor.

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