Does Lisinopril Cause Erectile Dysfunction? What You Need to Know

Lisinopril, an ACE inhibitor used to treat high blood pressure and heart conditions, typically does not cause erectile dysfunction (ED).
It's less likely to cause ED compared to other blood pressure medications like beta-blockers or diuretics.
However, individual reactions vary, and some men may still experience sexual side effects.
Are you concerned that your blood pressure medication might be affecting your sexual health?
If yes, read this blog, find out how Lisinopril compares to other drugs in terms of ED risk and what you can do if you’re experiencing symptoms.
About Lisinopril
Lisinopril is an ACE inhibitor to treat high blood pressure and heart conditions.
It works by relaxing blood vessels, lowering resistance, and improving blood flow.
Doctors commonly prescribe it for hypertension, heart failure, and recovery after a heart attack.
It may also have off-label benefits for conditions like diabetes, migraine, and diabetic retinopathy, as per some research.
Find out: Is it safe to take Lisinopril with Viagra?
What Are the Known Side Effects of Lisinopril?
According to the data from the FDA, these are some common side effects reported during the use of Lisinopril.
- Dizziness
- Headache
- Hypotension(Low blood pressure)
- Cough
- Syncope(Fainting or passing out)
- Hyperkalemia(High potassium levels)
If you have heart disease or heart failure, these side effects may become more prevalent while taking Lisinopril.
In case you suspect these symptoms, please consult a healthcare provider soon.
Find out which drugs may lead to erection problems among males.
Is Erectile dysfunction a side effect of Lisinopril?
Erectile dysfunction (ED) is not a common side effect of Lisinopril.
A study published in the American Journal of Hypertension compared Lisinopril and Atenolol in 90 hypertensive men aged 40–49.
Both groups experienced reduced sexual activity in the first month, but men on Lisinopril showed recovery over time, while those on Atenolol did not.
Only 3% of men on Lisinopril reported ED, compared to 17% on Atenolol.
The research suggests that Lisinopril may cause temporary sexual dysfunction initially, but is less likely to affect long-term sexual function.
Who Is at Higher Risk of ED When Taking Lisinopril?
Men are more likely to experience ED with Lisinopril if they are older, as age naturally lowers testosterone and affects blood flow.
People with diabetes or cardiovascular disease also face a higher risk due to already compromised vascular health.
Additionally, higher doses or long-term use of Lisinopril may increase the chance of experiencing erectile difficulties, especially if using other medications.
What to Do If You Have ED Symptoms While Taking Lisinopril
Erectile dysfunction can have many causes, and it’s not always easy to pinpoint the exact reason.
If you're consistently unable to achieve or maintain a penile erection, speak to your doctor; they may diagnose ED after assessing your symptoms.
Occasional erection issues are normal, but if the problem is ongoing, treatment options may include oral ED medications, lifestyle changes, or in some cases, devices or surgery.
Common ED Drugs like Vidalista (Tadalafil), Suhagra (Sildenafil), and Levitra are effective for many men.
Combining medication with regular exercise and a healthy lifestyle can further improve your sexual performance and help manage symptoms.
Always consult your doctor before starting ED treatment, especially while on medications like Lisinopril.
Final Lines:
Lisinopril Tablets are a commonly prescribed medication for high blood pressure.
While some men report erection issues early in treatment, studies suggest these effects are usually temporary.
Long-term use of Lisinopril is not strongly linked to chronic erectile dysfunction.
Identifying the exact cause of ED is essential for proper treatment and to reduce ongoing risk.
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Taking ED medication like Viagra while taking Lisinopril is likely to be safe. But one exception is nitrate, as using it with a PDE5 inhibitor may cause a severe fall in blood pressure. So taking nitrates with ED drugs is not recommended, and also, make sure to consult a doctor before you take these two drugs simultaneously.
Erectile dysfunction may appear as a common side effect of medicines that restrict or reduce blood flow. These medications include beta-blockers and thiazide diuretics, which may decrease blood pressure. Taking these drug may lower the blood flow to the penis and leads to issues with erection. And other blood pressure-lowering drugs that may rarely cause ED include alpha-blockers and ACE inhibitors.
Lisinopril is a first-choice medicine for high blood pressure(Hypertension) and is also prescribed for heart failure. A doctor may direct its use after a heart attack to help prevent the risk of strokes and heart attacks in future.
Lisinopril is an ACE inhibitor not used in the ED; it may help treat high blood pressure. However, several hypertension medicines may cause erection problems or worsen ED symptoms. So, it is less likely to help in erectile dysfunction unless the cause of ED is high blood pressure. In such cases, Lisinopril may be able to assist in the condition.
The use of Lisinopril may decrease plasma-free testosterone in males with Hypertension. But it may increase sex hormone-binding globulin(SHBG) in female hypertensive patients.